Present and future therapeutic strategies for melioidosis and glanders
نویسندگان
چکیده
منابع مشابه
Bichat guidelines for the clinical management of glanders and melioidosis and bioterrorism-related glanders and melioidosis.
Glanders and melioidosis are two infectious diseases that are caused by Burkholderia mallei and Burkholderia pseudomallei respectively. Infection may be acquired through direct skin contact with contaminated soil or water. Ingestion of such contaminated water or dust is another way of contamination. Glanders and melioidosis have both been studied for weaponisation in several countries in the pa...
متن کاملRecent Progress in Melioidosis and Glanders
B. pseudomallei and B. mallei can survive hostile conditions, becoming resilient to many antimicrobial agents, including antibiotics. In the paper by Rholl et al. (2011), the resistance to β-lactams, such as ceftazidime, was investigated. Genetic analysis of penA gene, encoding a putative twin arginine translocase (TAT)-secreted β-lactamase, demonstrated that PenA is secreted via the TAT system...
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Temperament (Mizaj), as an individual factor, has great importance in traditional medicine and its use in diagnosis and treatment of diseases, as well as the individual lifestyle is very common. Since medicine moves toward Personalized Medicine, the root of individual differences will find its position in different aspects of medicine in early future. In traditional medicine, temperament is ...
متن کاملBurkholderia pseudomallei and Burkholderia mallei: Melioidosis and Glanders
The genus Burkholderia is currently composed of many species, but only three are notable pathogens for humans or animals: the former cepacia complex (described in Chapter 220) pseudomallei (the agent of melioidosis), and mallei (the agent of equine glanders). All three are aerobic, nonsporulating, straight or slightly curved gram-negative bacilli that were formerly placed in the genus Pseudomonas.
متن کاملTuberculosis: Past, Present and Future
Background Tuberculosis (TB) is the second-most common cause of death from infectious disease (after those due to HIV/AIDS). Roughly one-third of the world's population has been infected with M. tuberculosis, with new infections occurring in about 1% of the population each year. People with active TB can infect 10-15 other people through close contact over the course of a year. Materials and ...
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ژورنال
عنوان ژورنال: Expert Review of Anti-infective Therapy
سال: 2010
ISSN: 1478-7210,1744-8336
DOI: 10.1586/eri.10.4